Organic Chemical Oxidations

Chemical and biochemical oxidations in spinal fluid after subarachnoid hemorrhage.

Subarachnoid hemorrhage (SAH) is a stroke with high rates of mortality and morbidity. SAH-induced cerebral vasospasm can lead to ischemic injury or death and is a common complication of SAH. Recently there has been an accumulation of emerging evidence that oxidation of heme-derived bilirubin into bilirubin oxidation products (BOXes) may be involved in cerebral vasospasm. BOXes are produced by t...

Organic Chemical Reactions

Aqueous Secondary Organic Aerosol Formation in Ambient Cloud Water Photo-Oxidations

The current understanding of aqueous secondary organic aerosol (aqSOA) formation is based largely on laboratory investigations of very simple surrogate cloud water solutions that aid mechanistic understanding of aqueous oxidation but may not accurately reflect the influence of the complex ambient matrix present in authentic cloud waters on organic chemistry. In this study, unaltered ambient clo...

Solvent-free, visible-light photocatalytic alcohol oxidations applying an organic photocatalyst

A method for the solvent-free photocatalytic conversion of solid and liquid substrates was developed, using a novel rod mill apparatus. In this setup, thin liquid films are realized which is crucial for an effective photocatalytic conversion due to the low penetration depth of light in heterogeneous systems. Several benzylic alcohols were oxidized with riboflavin tetraacetate as photocatalyst u...

Oxidations catalyzed by stable metallo-tetraaryl porphyrins under aqueous-organic two-phase conditions

Factors ruling the epoxidation of internal and ofd-olefins, catalyzed by chemically stable Mn(II1)tetraaryl porphyrins and promoted by HOCl and/or C10and by 30% H 0 are investigated in order to find conditions for large scale practical application. Reactions are carried out in CH C1 -H 0 at O°C, and are greatly enhanced by the presence of lipophilic imidazoles or pyridines as axial ligands on t...